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Selten, Monique M.A

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Sigma-Aldrich), DS18561882 (DS, HY-130251

The findings of this paper are strengthened using multiple mouse models to triangulate the consistent effect of amyloidogenic IAPP on APCs, including an unbiased scRNA-seq approach on an F1 FVB/NJ C57BL/6J genetic background, and similar protective phenotypes in two independent strains of congenic hIAPP-expressing NOD mice