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In animal models, combination therapy involving intra-tumoral CD delivery, systemic administration of 5-FC, and radiation demonstrated significantly improved anti-tumor effects, even though in vitro studies did not clearly show a synergistic relationship between radiation and genetically designed molecular therapy

Aging 34 , 26042612 (2013)

Similarly, Chinese herbal medicines that have played an active and significant role in the treatment of rheumatic diseases such as RA, such as Radix Gentianae Macrophyllae, Radix Stephaniae Tetrandrae, Caulis Sinomenii, and Caulis Lonicerae, have also become the targets for finding and screening new potential therapeutic agents for RA