glutathione pathway kegg Pathways Comparative transcriptome and metabolome analysis

Carr, [email protected] This article was submitted to Clinical and Translational Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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These KOs were also used for comparison among the other experimental groups, indicating consistent functional shifts by MZP treatment

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Additionally, direct measurements of ferroptosis-related endpointssuch as labile Fe 2 quantification, GSH/GSSG ratios, and protein-level expression of key markers (e.g., Western blot for GPx4 or SLC7A11)were not performed