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Role of Sirt1 plays in nucleus pulposus cells and intervertebral disc degeneration

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In addition to their role in gene regulation in cells, miRNAs are associated with various biological molecules, including proteins and lipoproteins, which increases their stability in the bloodstream [282]

if secondary antioxidant reserves become saturated, or decline, and primary antioxidant defences are compromised, oxidative stress can become excessive