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It has been reported that the prevalence of depressive and anxiety disorders and the associated disease burden increased significantly (more than 25% in the first year of the pandemic) worldwide during the COVID-19 pandemic [30]

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Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications (e.g., blood thinners) as well as those with a physician diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements

Significantly, the prevalence of sarcopenia is approximately 10%50% in people aged 60 years, which has become a serious challenge for global health (Witham and Aihie Sayer, 2016)

Acta 20 CaliT.OttoliniD.VicarioM.CatoniC.ValleseF.CieriD.et al (2019)