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YouMXieZZhangNZhangYXiaoDLiuSet alSignaling pathways in cancer metabolism: mechanisms and therapeutic targets

for instance, 10% PRP improved motility in buffalo bull semen and boer buck spermatozoa [26, 44], whereas 15% concentrations were more effective in human samples [24, 25, 48, 51]

Autophagy refers to the physiological and pathological processes of cellular lysosomal degradation, which are not only essential for cell survival and development but are also associated with various human diseases including diabetes (101103)

A study involving 20 men has found that 8-week aerobic exercise (treadmill training, 40 min, 3 times/week) significantly decreases serum ROS and neuron-specific enolase (NSE) levels, and increased SOD activity and brain-derived neurotrophic factor (BDNF) levels while improving body composition parameters in obese individuals, indicating that exercise can exert beneficial effects through improving the oxidant-antioxidant imbalance disrupted by obesity, elevating levels of neurotrophic factors, and limiting blood-brain barrier dysfunction [180]

10.1016/j.chroma.2017.05.062 146 WangY.TianY.ZhangN.LiX.WangX.WangW.et al (2021)