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HA could promote neurodevelopment and inhibit glial scars, thereby constructing an ideal biomimetic neural microenvironment for cell adhesion, growth, and differentiation, but a single collagen hydrogel had the tendency to shrink in vivo , destabilizing the ecological niche of cell growth (Zinger et al., 2021b)

Studies also demonstrated no significant inference of MTHFR C677T polymorphism in global DNA methylation in oral epithelial cell samples 31 or lymphocytes of healthy individuals 32 , as well as cutaneous squamous cell carcinoma in renal transplant patients 33

Healthcare Materials 13, e2303229

-Synuclein fate is determined by USP9X-regulated monoubiquitination

These findings are from cell studies and haven't been confirmed in a large human clinical trial, but the mechanistic logic is consistent