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Resistance to chemotherapy is associated with altered glucose metabolism in acute myeloid leukemia

Immunoreactivity of both SOD1 and SOD2, as well as catalase, is reportedly increased in regions of neurofibrillary tangles and plaques

However, under a tumorous environment, elevated expression of lysosome protease B can enzymolyze the two amide bonds of the link and cause cytotoxins to release in the complete active form

The translational value of targeting cuproptosis and copper metabolism lies in the identification of key regulatory molecules (e.g., FDX1, DLAT, ATP7A/B) and potential biomarkers (e.g., serum CP and NCC) that could guide clinical decision-making

Looking ahead: If the conflict continues to choke off oil shipments from Iran and other Gulf states, it could push oil prices even higher, analysts say