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Hainze, M., et al

It plays a crucial role in detoxifying harmful substances, fighting free radicals, and supporting the immune system

OROS Research products are not drugs, medications, dietary supplements, food products, cosmetics, or medical devices

elegans cannot de novo synthesize sterols as they lack genes for squalene synthase and cyclase (34), and they require dietary cholesterol for development (35)

LPS-induced miR-21-3p overexpression increased the protein and mRNA levels of the inflammatory cytokines monocyte chemoattractant protein-1 (MCP-1) and IL-6 in RPE cells while elevating apoptosis, caspase-3 activity, and levels of cleaved caspase-3 and poly-(ADP-ribose) polymerase proteins, which exacerbate inflammatory responses and apoptosis