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Next, the energy minimization step optimizes unreasonable conformations in the initial structure to avoid system collapse during the simulation

This concentration dependence could reflect the intermolecular nature of the rate-limiting propagation step of lipid autoxidation

The angle of repose () = tan -1 (h/r), where, h = height and r = the radius of the cone

Structural studies reveal that full-length human RAGE has three domains (Figure 4): an extracellular part responsible for ligand binding, a hydrophobic transmembrane spanning region, and a highly charged cytoplasmic tail, which is essential for RAGE ligand-mediated signal transduction (83, 87)

2009;4:e6344