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Fasting state and circadian timing significantly modulate GH response to secretagogue administration. Ho , Journal of Clinical Endocrinology & Metabolism Individual Adjustments Beginners should start at the low end of the dosing range (100 mcg 2x/day) to assess tolerance and response

doi: 10.1016/j.abb.2012.01.011 89 HuangJ.WangY.XieZ.ZhouY.ZhangY.WanX

However, research on ipamorelin is lacking and theres little definitive information available about the potential side effects or most advantageous doses for subjects

It binds to ghrelin receptors, stimulates the release of somatocrinin, and inhibits somatostatin and suppresses its action