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Swelling- and ROS-activated VSOR/VRAC anion channels were also implicated in pyroptosis (Green et al., 2018

Using mouse models in which loss of Hsp60 causes UPR mt activation and subsequent mitochondrial dysfunction specifically in intestinal stem cells (ISC) or IECs, we illustrated the crucial role of mitochondrial metabolism for intestinal stemness, Paneth cell functionality and the proliferative capacity of IECs 18,22,51

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Voice disturbances under stress overload and associated observations A recently performed clinical study suggested voice disturbances as an indicator of an individuals stress overload: the authors hypothesised that the voice perturbation in young (1922 years old medicine students) and otherwise healthy individuals might be positively associated with vascular dysregulation and dry mouth syndrome[15]