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Design, synthesis, ADME characterization and antileishmanial evaluation of novel substituted quinoline analogs

High concentrations for IV use should be diluted in normal saline or another compatible IV fluid before administration

Lean C57BL/6J mice and genetically obese (ob/ob) mice, all 12 weeks old, were divided into three treatment groups including: saline control, AOD9604 at a dose of 250 g/kg/day, and hGH at a dose of 1 mg/kg/day, with each group consisting of six mice

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