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Animal studies further highlight that prebiotic supplementation enhances detoxification enzyme activities and reduces oxidative stress markers in the liver, underscoring their therapeutic potential in liver health

Delayed complications occur weeks to years later, and include late-occurring nodules, dyspigmentation, and scarring

Management, therefore, focuses on identifying elevated Lp(a), intensifying control of all modifiable risk factors, lowering LDL-C or ApoB aggressively when appropriate, and considering PCSK9 inhibitor therapy in selected high-risk patients because monoclonal PCSK9 inhibitors modestly lower Lp(a) while substantially lowering LDL-C

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