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Ideal candidates typically include: Body composition goals: Individuals focused on reducing body fat percentage while preserving lean muscle mass, those who have reached plateaus with diet and exercise alone, patients seeking metabolically selective approaches without growth hormones broader effects, or individuals interested in targeted fat reduction (particularly abdominal/visceral fat)

TJs are comprised of various proteins traversing the intercellular cleft such as occludins and claudins, which are further linked to important scaffolding proteins as well as other regulatory proteins like cingulin, ZO-1, ZO-2, and ZO-3 [21]

Free Radic Biol Med 46: 44353

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& Hislop, A