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They also inhibit neural cell necrosis and induce the proliferation of astrocytes

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Given the presence of both mandatory major criteria (polyneuropathy and monoclonal plasma cell proliferative disorder), at least one other major criteria (sclerotic bone lesions), and at least one minor criteria (skin changes, extravascular volume overload, endocrinopathy), as well as other associations (vitamin B12 deficiency), the patient was diagnosed with POEMS syndrome