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Male mice (21-24 weeks old) were fed with Western diet and a high fructose-glucose water (WDSW) or chow diet ad libitum for 6 months or 1 year

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5 IF regulates ceramides profiles and mitochondrial function and dynamics 5.1 Effect of IF on ceramides levels and lipid composition in the mitochondria membranes As mentioned above, IF and CR have been demonstrated to modify mitochondrial function, however, little is known regarding the effects of these dietary regimens on mitochondrial membrane composition