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Various stimuli, including telomere dysfunction and oxidative stress, induce cellular senescence through the p53 and Rb proteins, and senescent cells can promote disorders associated with aging or age-related diseases

Cancer promotion concerns arise from IGF-1's well-established role in cellular proliferation, survival, and growth

Because KAT6A contains multiple functional domains, it is possible that ARTHS variants may result in a truncated protein that retains acetyltransferase activity but lacks proteinprotein interaction domains that regulate this activity

Either or both of these things may lead them to discontinue the medication

Nanomaterial-based CT contrast agents and their applications in image-guided therapy