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At the same time, elevated tumor GSH can be exploited as a conditional trigger for prodrug activation, nanomedicine-based delivery, or metal-driven cytotoxicity, thereby converting a classical resistance factor into a therapeutically actionable vulnerability

In addition, normalization for Hb also allows for the analysis of GSH in blood samples of unknown volume

Though these latter treatments are also useful, they would typically take much longer to affect the results and are less potent than intravenous treatments

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Absorbance of the reaction was detected at 595 nm by a microplate reader (Spectra MR, DYNEX Technologies, USA) and the total protein content was expressed as milligrams of BSA equivalent per gram of APE (mg BSA/g APE) 33