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Retatrutide is an investigational peptide drug currently under clinical development by Eli Lilly

Changes to the microbial phyla and genera observed in the 5A-1MQ-treated group switched from WD to LD could have been driven by additive, synergistic, or independent mechanisms relative to those induced by diet switch alone, which could not be determined with the current study design that lacked a group treated with 5A-1MQ and maintained on WD

In limited data it's generally reported as well-tolerated, but human safety data is still limited and long-term effects aren't fully characterized

Most recommendations suggest consuming at least 0.7 to 1 gram of protein per pound of body weight daily

DIO control mice, JAX cat no