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30 , 462476.e466 (2019)

Fold change in DiI-labelled LDL (c) and HDL (d) uptake of A-498 cells upon treatment with heparinases (0.1 U/mL), chondroitinase (0.1 U/mL), or both (blue), relative to uptake of untreated cells

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While further research is needed, researchers have found links between lower glycine levels in the blood and higher risks of high blood pressure and heart disease

This includes increased phosphorylation of dynamin-related protein 1 (DRP1) at serine-616, promoting mitochondrial fragmentation, and decreased expression of fusion proteins such as mitofusins (MFN1/2) and optic atrophy 1 (OPA1) (Andreazza et al., 2010