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Chronic treatment with the ACE inhibitor enalapril attenuates the development of frailty and differentially modifies pro- and anti-inflammatory cytokines in aging male and female C57BL/6 mice

Although NLC-LC yielded the highest numerical value, the lack of statistical significance versus free LC indicates that nanoencapsulation did not provide a detectable additional benefit on progressive motility under the conditions tested (0.5 mg/mL equivalent LC, 1 h exposure)

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renal impairment can further exacerbate neuropathic symptoms through the accumulation of uremic toxins that adversely affect nerve function

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