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Gut microbiota-derived 3-hydroxybutyrate blocks GPR43-mediated IL6 signaling to ameliorate radiation proctopathy

Improvements were seen not only in facial function, but also in nerve conduction studies, providing physiological support for its effect

This promises to reveal the conditions under which plasticity in the visual pathway can be maintained or even induced: this would open up the possibility whereby modulation of "molecular switches" with specific drugs could allow or facilitate the regeneration of damaged pathways

These findings could mark a major advancement in the treatment of CHB, offering patients a more effective strategy to manage the disease