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The recommended dosage of Pemetrexed Injection for maintenance treatment of non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m2 as an intravenous infusion over 10 minutes on Day 1 of each 21-day cycle until disease progression or unacceptable toxicity after four cycles of platinum based first-line chemotherapy

doi: 10.3390/oxygen2020006 [DOI] [Google Scholar] 72

Especially from the age of 40, they are an unloved companion on our face, hands, arms or shoulders

Allergic-type Reactions: Anaphylaxis (in severe cases) Swelling of the lips, tongue, or throat Difficulty breathing Rapid heartbeat 6