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Cagrilintide comes at appetite from the amylin side, a hormone pathway that the GLP-1 drugs barely touch

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Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY

doi: 10.3389/fimmu.2023.1183331 128 WeeksD

Current clinical or preclinical data suggest that long-acting amylin analogues have the potential to achieve weight loss equivalent to that of GLP-1 receptor agonists but with better tolerability, providing a better experience for patients and achieving high-quality weight loss by preserving lean muscle mass