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EE was calculated using the Weir equation for respiratory gas exchange measurements

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Deficiency symptoms often manifest as hair thinning, brittle texture, and premature greying, as B12 is necessary for melanin production in hair follicles

Dowd, P., Hershline, R., Ham, S

1.2 Regulatory mechanisms of ferroptosis The central feature of ferroptosis is redox imbalance (9), and its regulatory network involves multiple metabolic pathways (Figure 1), which show uniqueness in highly metabolic tissues, such as the ocular retina