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after removing two conference abstracts, one editorial, and one duplicate, 104 records proceeded to screening

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Telmisartan attenuates diabetic nephropathy by mitigating oxidative stress and inflammation, and upregulating Nrf2/HO-1 signaling in diabetic rats

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Specifically, chronic inflammation in RA can lead to long-term changes in the central nervous system (CNS), resulting in heightened pain sensitivity (hyperalgesia) and pain from non-painful stimuli (allodynia) (Sa et al., 2020