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Several clinical studies over the past two decades have demonstrated that: Glutathione is severely depleted in patients with Parkinsons and other neurodegenerative diseases

As liver function gradually deteriorates and fibrosis develops, highly lethal cirrhosis may be induced and prognosis becomes increasingly challenging (171)

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In addition, deoxy-arbutin is a dose-dependent tyrosine hydroxylase inhibitor which can further inhibit the melanogenesis process

Typically, serological patterns of type 1 and 2 AIH are mutually exclusive, but can co-exist in a proportion of pediatric cases making it difficult to classify the patient as type 1 or 2 [4]