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Analyses of centella material put Asiatic Acid reported in the range of 0.2-3% of the extract

Serine, either supplemented to a 0.5, 1, or 2% Met diet for 10 days or injected intraperitoneally with Met (100, 200, 300, or 500 mg/kg), was able to significantly reduce Hcy levels in rats

24 Hyperammonaemia without clinically significant liver injury has been very well studied and is most likely linked to mitochondrial dysfunction

doi: 10.1038/s41591-020-1023-0 26 TsikasD

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