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Just a few examples of specific PAMPs that TLRs can identify and bind to include:6,7,8,9 Bacterial lipopolysaccharide (LPS): A toxin found on membranes of gram-negative bacteria Lipopeptides: Structurally-diverse metabolites produced by bacteria and fungi which help them during the colonization of new habitats and during the formation of biofilms Lipoteichoic acid: Cell wall component of gram-positive bacteria that plays important roles in infection and inflammation Peptidoglycan: A bacterial cell wall component Bacterial flagellin: A globular protein that is a significant contributor to bacterial invasion, and has also emerged as a potent immune activator Now lets zoom in on exactly what happens once these PAMPs bind to your TLRs and how these specialized receptors help your body fight infections

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