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Monitor closely for hypothalamic amenorrhea, a condition where excessive energy deficit suppresses the hypothalamic-pituitary-gonadal axis

It presents with a broad clinical spectrum, ranging from asymptomatic or non-specific symptoms, such as fatigue or lightheadedness, to severe manifestations, including nausea, vomiting, alteration of consciousness, and even coma, which can be life-threatening 3,4

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By blocking NNMT, 5-Amino-1MQ helps preserve NAD, which supports metabolism, energy production, and cellular repair

AOD-9604 enhances the rate and efficiency of fat cell mobilization, but a net caloric deficit is still required for meaningful fat loss