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Acetyl-L-carnitine (ALCAR) (500mg per serving) ALCAR is a mitochondrial cofactor that plays a key role in cellular energy production and nerve cell maintenance.48 Its been shown to improve nerve regeneration and reduce neuropathic pain in people with diabetes, particularly at daily doses of 1,0002,000mg.49 While Nerve Defend provides a lower dose, combining ALCAR with ALA and NAC may enhance its therapeutic effect.63 64 N-acetylcysteine (NAC) (600mg per serving) NAC is a precursor to glutathione one of the bodys most important antioxidants.50 In the context of diabetic neuropathy, oxidative stress plays a major role in nerve damage

doi: 10.1002/bit.21256 27 LiuS.YiH.ZhanH.WangL.WangJ.LiY.et al

Rather, it appears to stem from diminished interactions between ATG2A and ZDHHC11

Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons

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