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Nualart et al., 2012

Rizzo C, Ribes A, Pastore A, Dionisi-Vici C, Greco M, Rizzoni G, Federici G

doi:10.1073/pnas.0908786106 Iwasaki S, Yamasoba T

Glia 50 , 276279 (2005)

Results A forward genetic screen identifies unc1 as a modulator of polyQ aggregation To expand our knowledge of the signalling pathways controlling protein homeostasis, we performed a chemical mutagenesis screen for genes regulating protein aggregation in a worm model of polyQ diseases