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Embryofetal Toxicity Some epidemiologic studies suggest that exposure to sulfamethoxazole/trimethoprim during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot

Transforming growth factor- (TGF-) regulates cell fate specification and tissue morphogenesis

102 The results of clinical trials support the usefulness of oral administration of NAC, generally 600 mg/day, in chronic bronchitis and COPD patients to prevent exacerbations

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