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The cysteine S -conjugates may (1) react directly with DNA, (2) generate reactive oxygen species, or (3) be further transformed to insoluble polymers (possibly involving cyclization reactions) that cause local irritation and cell proliferation (Monks and Lau, 1994)

GSTM2 overexpression suppresses hepatic steatosis Although GSTM2 was up-regulated in mice with hepatic steatosis, we also overexpressed this protein in mouse model fed with MCDD (Supplementary Fig

Neuroprotection Mechanism: Pinealon has been shown to counteract damage caused by toxins (EX: Homocysteine), which are linked to Alzheimer's and vascular pathology

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