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SKU: 8440635216
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Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma

doi: 10.1016/j.it.2018.10.009 82 BlancCHansSTranTGranierCSaldmanAAnsonMet al

Concurrently, ferroptosis reprograms TAMs, shifting them from immunosuppressive M2- to pro-inflammatory M1-phenotypes via iron overload, ROS accumulation, and modulation of GPX4, NF-B, xCT, and TLR2 signaling [110, 111]