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In animal models, exposure to lead acetate led to inhibition of ALAS in blood, activation of plasma CAT, elevation of MDA and GSSG, reduction in the level of plasma GSH, and an increase in oxygen free radicals ( Figure 1 ) [64]

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Glutathione peroxidase activity in bovine serum and erythrocytes in relation to selenium concentrations of blood, serum and liver

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Cysteines rapidly undergo auto-oxidation and form disulfide bonds with other cysteines(i.e., cystine), a process that is further accelerated by transition metal ions like copper and iron [115,116]