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[4] Ultimately, the choice of GLP-1 agonist should be a collaborative decision between the patient and their healthcare provider, taking into account individual factors, treatment goals, and potential risks and benefits

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Both genetic ablation and chemical inhibition of TRF1 telomeric localisation can block the growth of p53-null K-Ras G12V -induced lung carcinomas and PDGFA/B-induced glioblastomas in a telomere-length independent manner, remarkably without affecting mouse survival or tissue function 1,2,3

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and one published human clinical study examining intra-articular injection in 12 patients with chronic knee pain, of whom 7 out of 12 reported relief lasting over 6 months [15]