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Interestingly, Peleg and colleagues found that old mice have deregulated H4K12ac levels in certain key genes, impairing their ability to learn (Peleg et al., 2010)

Dysregulation of Pin-1 has been associated with cancers and Alzheimers disease (reviewed in Guito and Lukac, 2015)

Zhuang Y, Wu H, Wang X, He J, He S, Yin Y

Certain medical conditions, such as pernicious anaemia, can also affect a persons absorption of vitamin B12 from foods

soluble CLIC1 undergoes a transition to a membrane-bound form through oligomerization followed by the formation of an intramolecular disulfide bond (Cys24-Cys59) 12,14