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Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women

In cases of Hashimotos, the immune system perceives thyroid proteins as harmful, releasing antibodies in its defense

Similarly, in dogs with IBD compared with normal controls, the expression of the protein E-cadherin was lower in the villus epithelium, suggesting the role of this protein in the pathogenesis of IBD in dogs [80]