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1 Introduction Neurodegenerative diseases are irreversible disorders of the nervous system caused by progressive loss of neurons in the brain and spinal cord ( In recent decades, studies have identified several key factors contributing to neurodegeneration, including inflammation, aging, oxidative stress, and genetic mutations ( Over the past few decades, multiple modes of cell death have been defined

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And I will just say one additional thing about this: if you wake up in the morning, you know, and you didn't get enough sleep