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Mechanism four (mast cell and histamine) : MCAS, IBS, interstitial cystitis, POTS, Ehlers-Danlos syndrome, fibromyalgia, chronic Lyme, mold illness, neurological development disorders, nervousness disorders, and low mood

Reduced glutathione can either scavenge superoxide and hydroxyl radical non-enzymatically or by serving as an electron-donating substrate to several enzymes involved in ROS-detoxification (reviewed in [126])

Likewise, the addition of licorice juice can mitigate the metabolic disturbances in amino acid, organic acid, and ketone metabolism induced by Aconiti Radix Lateralis Praeparata (Fuzi) in rats, suggesting that modulation of energy metabolism and ketone body pathways may be another important mechanism underlying the detoxifying effect of licorice juice processing exerts [186, 187]