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Astrocytic chaperones and Parkinson Chaperones belonging to the conserved family of Heat shock proteins (Hsps) are proteins involved in the regulation of protein folding, translocation of proteins across membranes, regulation of cell death and assembling of protein [114]

The single most common source of disappointment with a compound like KLOW is expecting a fast, dramatic, visible change

This number of observed edges was significantly greater than expected for a random network of similar size (P1x10-16), indicating that the encoded proteins are more interconnected than would occur by chance and are likely involved in biologically related processes

A., Dubowchik, G

The lactate produced by glycolysis is then transported out of astrocytes through monocarboxylate transporters (MCT1 and MCT4) and taken up by neurons via MCT2 (Figure 1)