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Therapeutic targeting of glutamate dehydrogenase 1 that links metabolic reprogramming and Snail-mediated epithelialmesenchymal transition in drug-resistant lung cancer

Caenorhabditis elegans , a pluricellular model organism to screen new genes involved in mitochondrial genome maintenance

For in vivo antitumor experiments of subcutaneous xenograft animal model, mice were randomized on the basis of the tumor size before administration to ensure similar average tumor sizes across groups, and five mice were included within each group to ensure statistical power, which enabled us to statistically distinguish tumor sizes and survival rates across groups

McCord, J.M., Keele, B.B

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