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Growth hormone secretagogues produce full-spectrum growth hormone effects including potential appetite stimulation, IGF-1 elevation, and systemic metabolic changes affecting multiple tissues

The senescence problem To appreciate the significance of FOXO4-DRI, it helps to understand cellular senescence and why it matters in ageing and disease

Supplemental Figure Acknowledgments We express our thanks to professor Huiliang Li (Wolfson Institute for Biomedical Research, UCL) for his helpful discussion of the project, critical reading and kind suggestions to the manuscript

An increase in the activity of matrix-metalloproteases (MMPs) or an increase in neuronal glucose uptake are two likely mechanisms by which inhibition of IRAP can provide an enhancement of memory

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