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8A, mice were randomly assigned to three groups (PBS, DOX, and MND-ART-GEL

After injection, the most common side-effects were pain or injection-site reactions (all of mild intensity)

This phenomenon, known as metabolic endotoxemia, has been linked to: Chronic inflammation Insulin resistance Obesity Metabolic syndrome In animal studies, even modest increases in circulating endotoxins have been shown to trigger inflammatory responses that interfere with metabolic regulation

But if toxic impairment has not been tested for and corrected, other therapies such as counseling may not be effective until eliminating the toxic burden

In one aspect, an antigen is used for which a convenient means of detection is available