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b) Specific components: These proteins are unique to the parent cells from which the Exos are derived and are closely associated with their cellular origin

, AndrMiral C., NasreNasser R

32 Whether these specialized forms of PS externalization lead to diverse depots of PS on the membrane is not clear, although the recent development of high-resolution fluorescent probes, such as Disciodin-C2, and GFP-LactadherinC2, should make it more feasible to visualize PS in discrete subcellular membrane domains and topologies

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Farnesylation, cholesteroylation, glycosylphosphatidylinositol modification, irreversible fatty acylation (myristoylation) and reversible fatty acylation (palmitoylation) are the best studied types of lipid modifications [2527]