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Total cholesterol levels at the end of our study in the control DIO mice were comparable to cholesterol levels reported by the vendor for age-matched DIO mice

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Phase 1 dose-escalation study of pegylated arginine deiminase, cisplatin, and pemetrexed in patients with argininosuccinate synthetase 1-deficient thoracic cancers

Synthetic anticholinergics subsequently became the principal drugs to treat PD in the first half of the twentieth century and were joined by amantadine as a second non-dopaminergic agent in the late 1960s [131, 132]

BV, alone or in combination with other compounds, significantly increased apoptosis (as indicated by upregulation of the pro-apoptotic marker Bax and downregulation of the anti-apoptotic marker Bcl-2) and decreased the mRNA level of the BC-related receptors ER and EGFR in the two BC cell lines T-47D and MCF7 [40]