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In the further studies, we noted that many other herbal medicines ( Coptis chinensis Franch , Phellodendron amurense , and Berberis sargentiana Schneid , et al.) also reportedly contain some of the same alkaloids compared with FRP (Wang et al., 2009

MH received clinical trial materials and funding from Janssen Pharmaceutica NV for work related to this trial

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 30% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Over six months, this approach results in an average weight loss of 810%, equivalent to 810 kg for most patients

Neurology 35:10571058