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006852, The Jackson Laboratories) mice were used for in vitro circadian synchronization experiments

Comments submitted after July 9 but before the July 22 docket closure will still be considered by FDA, but will not go directly to the Committee

Cell death induction and inhibition Cells seeded at 1 10 5 per well in a 12-well plate with medium supplemented with 2% FBS were pre-treated with the inhibitors QVD-Oph (pan-caspases inhibitor, 10 M), Necrostatin-1 (RIPK1 inhibitor, 40 M), Ferrostatin-1 (ferroptosis inhibitor, 5 M), Sulfo-N-succinimidyl Oleate sodium (CD36 inhibitor, 100 M)